David Raskin, Ph.D.

Investigator Page


Ph.D. from Case Western Reserve University, 2001 in molecular biology & microbiology;  Postdoctoral (Ellison Medical Foundation Fellow of the LSRF) with Dr. John Mekalanos, Harvard Medical School, 2008

Research Interests:

Bacterial Pathogenesis, Microbial Stress Responses

Research Projects:

  • Pathogenesis of Vibrio cholerae, the causative agent of cholera
  • Effects of aquatic and human environments on virulence gene regulation in V. cholerae
  • Microbial Stress Responses in V. cholerae and Pseudomonas aeruginosa
  • Biofilm formation

Representative Publications

Oh, Y.T., Lee, K.-M., Bari, W., Raskin, D.M., Yoon, S.S. 2015. A small nucleotide regulator, (p)ppGpp, directs the metabolic fate of glucose in Vibrio cholerae. J. Biol. Chem. 290:13178-13190.

Oh, Y.T., Park, Y., Yoon, M.Y., Bari, W., Go, J., Raskin, D.M., Lee, K.-M., Yoon, S.S. 2014. Cholera toxin production during anaerobic Trimethylamine N-oxide respiration is mediated by stringent response in Vibrio cholerae. J. Biol. Chem. 289:13232-13242.

He, H., Cooper, J.N., Mishra, A. and Raskin, D.M. 2012. Stringent response regulation of biofilm formation inVibrio cholerae. J. Bacteriol. 194:2962-2972.

Raskin, D.M., Judson, N., and Mekalanos, J.J. 2007. Regulation of the stringent response is the essential function of the conserved bacterial G protein CgtA in Vibrio cholerae. Proc. Natl. Acad. Sci. USA 104:4636-4641.

Raskin, D.M., Seshadri, R., Pukatzki, S.U., and Mekalanos, J.J. 2006. Bacterial genomics and pathogen evolution. Cell 124:703-714.

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